4 doctors weighed in:

Is it possible for polycythemia rubra vera to begin with an anemia?

4 doctors weighed in
Dr. Edward Neilsen
Family Medicine
2 doctors agree

In brief: No....yes

Intuitively i would say no.
..The disease itself is classified by having too many red blood cells. However, i did discover a clinical scenario (http://www.Medscape.Com/viewarticle/410587) where this was thought to be the case. Just as sugars may fluctuate before developing diabetes and the TSH often bounces around before hypothyroidism....Anything is possible.

In brief: No....yes

Intuitively i would say no.
..The disease itself is classified by having too many red blood cells. However, i did discover a clinical scenario (http://www.Medscape.Com/viewarticle/410587) where this was thought to be the case. Just as sugars may fluctuate before developing diabetes and the TSH often bounces around before hypothyroidism....Anything is possible.
Dr. Edward Neilsen
Dr. Edward Neilsen
Thank
Dr. Liawaty Ho
Internal Medicine - Hematology & Oncology

In brief: Case reports

Majority of polycythema rubra vera (prv) is associated with the presence of too much red blood cells.
To produce those red blood cells- body needs to have enough nutritions- ie. Iron, folic acidl vit B12 etc. There have been cases where patient is presented with anemia due to vit B12 deficiency that is masking prv. Also, prv can lead to anemia- when the prv transforms into myelofibrosis/leukemia.

In brief: Case reports

Majority of polycythema rubra vera (prv) is associated with the presence of too much red blood cells.
To produce those red blood cells- body needs to have enough nutritions- ie. Iron, folic acidl vit B12 etc. There have been cases where patient is presented with anemia due to vit B12 deficiency that is masking prv. Also, prv can lead to anemia- when the prv transforms into myelofibrosis/leukemia.
Dr. Liawaty Ho
Dr. Liawaty Ho
Thank
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