What are the best ways of increasing HDL levels to 45 or above?

Exercise. There are several ways of raising your hdl. First is exercise, which can raise your HDL by 5% or more. Modest amount of alcohol can also raise your HDL slightly. Niacin in therapeutic doses can also raise your hdl. But Niacin in high doses can cause flushing, which can be uncomfortable.
Diet & exercise. Moderate exercise (about 30 minutes five times a week) reduces LDL cholesterol and raises HDL cholesterol. Smoking can lower HDL levels, so stop smoking if you do. Eat lots of fruits, vegetables, whole grains and lean sources of protein. Include monounsaturated fats in your diet- olive oil/canola oil. Moderate consumption of alcohol may also positively impact HDL levels. 1 glass of wine a day.