11 doctors weighed in:

Do antibiotics effect the effectiveness of mirena (levonorgestrel)?

11 doctors weighed in
Dr. David Finke
Obstetrics & Gynecology
6 doctors agree

In brief: Not really

Mirena (levonorgestrel) is a progesterone-secreting iud (intrauterine device).
The Progesterone is distributed systemically through the body and is metablized by the liver. Some drugs, including antibiotics can speed up the metabolism of the progesterone, but this shouldn't decrease it's effectiveness. Theoretically, you may get spotting. It also acts to prevent implantation, which is not affected by antibioti.

In brief: Not really

Mirena (levonorgestrel) is a progesterone-secreting iud (intrauterine device).
The Progesterone is distributed systemically through the body and is metablized by the liver. Some drugs, including antibiotics can speed up the metabolism of the progesterone, but this shouldn't decrease it's effectiveness. Theoretically, you may get spotting. It also acts to prevent implantation, which is not affected by antibioti.
Dr. David Finke
Dr. David Finke
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Dr. Scott Kramer
Gynecology
3 doctors agree

In brief: No

The Mirena (levonorgestrel) iud works as a contracpetive primarily by its presence inside the uterus.
The progestin enhances the effectiveness (99%) and also gives the benefit of lighter periods. Antibiotics that might affect the processing of oral contraceptives (hormones) have no effect on the progestin from the iud because it's already inside the uterus where it works.

In brief: No

The Mirena (levonorgestrel) iud works as a contracpetive primarily by its presence inside the uterus.
The progestin enhances the effectiveness (99%) and also gives the benefit of lighter periods. Antibiotics that might affect the processing of oral contraceptives (hormones) have no effect on the progestin from the iud because it's already inside the uterus where it works.
Dr. Scott Kramer
Dr. Scott Kramer
Thank
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