What are the long term effects of excedrin?

Dose dependent. Excedrin is a combination of Acetaminophen (tylenol) Aspirin and caffeine. Acetaminophen is recommended to mot exceed 300mg/day. Aspirin can cause ulcers and bleeding. Caffeine is a stimulant. People who are taking "blood thinners" should discuss the use of Aspirin with their physicians. If you are taking this or any pain product for long term, you should discuss this with your physician.

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