13 doctors weighed in:
About the brca-1 gene (breast cancer gene)...If a male is a carrier for the gene what will happen to his daughters?
13 doctors weighed in

Dr. Barry Rosen
Surgery
8 doctors agree
In brief: 50:50 inheritance
Any child of a brca carrier has a 50:50 chance of inheriting that mutation.
If they have inherited the mutation, they have a 50-80% chance of developing breast cancer, and an increeased risk of several other cancers. For more information, check this link: http://www.Cancer.Gov/cancertopics/factsheet/risk/brca.

In brief: 50:50 inheritance
Any child of a brca carrier has a 50:50 chance of inheriting that mutation.
If they have inherited the mutation, they have a 50-80% chance of developing breast cancer, and an increeased risk of several other cancers. For more information, check this link: http://www.Cancer.Gov/cancertopics/factsheet/risk/brca.
Dr. Barry Rosen
Dr. Barry Rosen
Thank
Dr. Devon Webster
Internal Medicine - Oncology
4 doctors agree
In brief: 50% chance
Each child of a father carrying a brca mutation has a 50% chance of having the same mutated gene.
If a daughter has the brca1 mutation, she will have a higher chance of developing breast and ovarian cancer at an early age. Any child of a parent with a brca mutation should have genetic counseling and testing before childbearing age.

In brief: 50% chance
Each child of a father carrying a brca mutation has a 50% chance of having the same mutated gene.
If a daughter has the brca1 mutation, she will have a higher chance of developing breast and ovarian cancer at an early age. Any child of a parent with a brca mutation should have genetic counseling and testing before childbearing age.
Dr. Devon Webster
Dr. Devon Webster
Thank
Dr. Carlos Encarnacion
Internal Medicine - Oncology
2 doctors agree
In brief: 50%
Each child of a brca mutation carrier has a 50/50 chance of getting the mutation regardless of gender. We usually test them for only that particular mutation (single site analysis) which is cheaper. Word of warning: two individuals with two different mutations can be married and then each child can inherit none, one, or both.
We need to know the family history of both sides of the family.

In brief: 50%
Each child of a brca mutation carrier has a 50/50 chance of getting the mutation regardless of gender. We usually test them for only that particular mutation (single site analysis) which is cheaper. Word of warning: two individuals with two different mutations can be married and then each child can inherit none, one, or both.
We need to know the family history of both sides of the family.
Dr. Carlos Encarnacion
Dr. Carlos Encarnacion
Thank
Get help from a real doctor now
Dr. Crystal Twynham
Board Certified, Surgery
29 years in practice
938K people helped
Continue
107,000 doctors available
Read more answers from doctors