2 doctors weighed in:

Can clinical depression cause brain damage? Kindly advice

2 doctors weighed in
Dr. Louis Cady
Psychiatry
1 doctor agrees

In brief: Depression & brain

Quick answer: yes.
(although the brain damage would be considered "mild" compared to a stroke or brain trauma). Chronic depression lowers the secretion of brain derived neurotrophic factor ("bdnf") in the brain. This is active in the hippocampus (where memory function lives), cortex and the basal forebrain. This compound plays a significance role in maintenance and surrival of your neurons.

In brief: Depression & brain

Quick answer: yes.
(although the brain damage would be considered "mild" compared to a stroke or brain trauma). Chronic depression lowers the secretion of brain derived neurotrophic factor ("bdnf") in the brain. This is active in the hippocampus (where memory function lives), cortex and the basal forebrain. This compound plays a significance role in maintenance and surrival of your neurons.
Dr. Louis Cady
Dr. Louis Cady
Thank
Dr. Alan Ali
Psychiatry

In brief: Depression

Short answer is no. No structural damage.

In brief: Depression

Short answer is no. No structural damage.
Dr. Alan Ali
Dr. Alan Ali
Thank
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