Vaginal itching (both libias, vaginal opening -not inside, just around the hole. I have hsv1-2 I've taken my medication and nothing has gone away.

May not. Treatment of herpes infection affecting the genitals may not respond rapidly to therapy with Acyclovir when you have active lesions to begin with. These may have to run their course, although generally treatment will shorten the duration of illness. Sometimes it is just poorly effective.
May be resistant. Herpes to the med u are on or something else u need to see your gyn for an exam and culture, I use a lab on my pts that can culture for as many organisms as I need to check for with just one swab when my pts in coral springs fl need that.