4 doctors weighed in:

How does dengue fever leads to hepatomegaly?

4 doctors weighed in
Dr. John Fung
Surgery
2 doctors agree

In brief: Multiple factors

Clinical evidence of liver involvement in dengue infections includes the presence of hepatomegaly and increased serum liver enzymes.
Dengue viral antigens have been found within hepatocytes, and the virus appears to be able to replicate in both hepatocytes and kupffer cells, and dysregulated host immune responses may play an important causative role in liver damage.

In brief: Multiple factors

Clinical evidence of liver involvement in dengue infections includes the presence of hepatomegaly and increased serum liver enzymes.
Dengue viral antigens have been found within hepatocytes, and the virus appears to be able to replicate in both hepatocytes and kupffer cells, and dysregulated host immune responses may play an important causative role in liver damage.
Dr. John Fung
Dr. John Fung
Thank
Dr. James Loflin
Urgent Care

In brief: Liver Infection

The dengue virus infects the liver cells.
Google pathogenesis of liver involvement during dengue viral infections.

In brief: Liver Infection

The dengue virus infects the liver cells.
Google pathogenesis of liver involvement during dengue viral infections.
Dr. James Loflin
Dr. James Loflin
Thank
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