What does red and black spots in sputum indicate?

Sputum. A common cold, nose bleed, dry mucosa with capillary bleeding, cancer, stomach- lung- throat issue, etc. ...

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What do red and black spots in sputum indicate?

Blood. Sputum/phlegm can sometimes be blood streaked (red spots); if the bleeding has been there for some time the blood will become dark brown/black. Some infections can change the color of the sputum as well.