Low rbc, low hgb, high mcv, normal iron & B12 levels. What is the cause of anemia?

Macrocytic anemia. The most common causes of macrocytic anemia are B12 (ruled out for you) and folate (folic acid) deficiencies. Folate (folic acid) deficiency can be caused by diet (very rare - folate (folic acid) is everywhere), celiac disease, alcoholism, or hemolysis (autoimmune process, for example). Rarer causes include aplastic anemia and myelodysplastic syndrome (mds). If not clear to your doc, may need to see hematologist.
Multiple possible. If a patient has had recent surgery, that might be the cause. B12 and Folic Acid deficiencies can cause a high MCV (ie, it can represent a nutritional cause). Other possibilites include hemolysis (breaking of red blood cells), kidney disease and other chronic diseases.

Related Questions

5 year old has persistent normocytic anemia. High WBC, platelets, low RBC and hemoglobin. Normal MCV, MCH, ferritin and reticulocyte. What's the cause?

Need more tests,,, This is hard to determine as this is the case of a child. Other tests like a peripheral blood smear might help to find the cause. It would be best to see the doctor, preferably a pediatrician, for more tests and an exam. Best of luck. Read more...

Recent blood work. Wbc, Rbc, hgb, hct, mcv normal. Low mchc. High Rbw. What does this point to? Had iron def anemia in past.

You can look these. all up, e.g. http://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin_concentration, http://en.wikipedia.org/wiki/Red_blood_cell_distribution_width, etc. If the MCV is ?er Nl, combined with ?ed MCHC these could be c/w some mild Fe deficiency currently. If Reticulocyte count is elevated, this would be c/w the?ed RDW due to an ?ed mix of younger, immature plus older cells. These values just clues. Read more...