How can you most effectively remove head lice?

Special shampoo. Your doctor will recommend a special shampoo designed to kill the lice and nits. Some of these are over the counter while others need a prescription. After using the shampoo the lice will be killed but it may take a few days for the itching to stop.
Lice . Tx of lice requires accurate identification of nits & lice. A pediculicide is usually used- OTC like Nix or RID or prescription meds like lindane or malathion. Work carefully through hair & remove individual nits. Purchase a special lice nit comb to aid you. Check for nits & remove as seen over the next 7 to 10 days. If there are nits after 7 to 10 days – a 2nd pediculicide tx may be needed.