For last two days I been waking up with heartburn I took Prilosec and protonix (pantoprazole) its not going away what could this be my stomach dosent hurt just chest?
If it is reflux. The proton pump inhibitors help if you take them in the evening, as gerd is worst at night. Your history sounds consistent.
Gerd not responding to Prilosec or protonix (pantoprazole).....Burning in chest, back throat. Could this be something else? Will I ever be able to get off a ppi?
Hopefully. If you are significantly overwight, your chances of getting off ppi drugs will be helped by weight loss and multiple small meals rather than a couple of large ones. Avoidance of alcohol, tobacco, caffeine, and anticholinergic drugs can help too.