1 doctor weighed in:

Can you have lupus if your ANA come back negative?

1 doctor weighed in
Dr. Larry Greenbaum
Internal Medicine - Rheumatology

In brief: Unlikely, but...

The ANA is a very sensitive test, so it tends to have too many false positives, rather than false negatives.
Textbooks talk about lupus with negative ANA results, but i suspect this is only a tiny percentage of lupus patients. Sometimes other labs or procedures can be helpful. Speak to your doctor.

In brief: Unlikely, but...

The ANA is a very sensitive test, so it tends to have too many false positives, rather than false negatives.
Textbooks talk about lupus with negative ANA results, but i suspect this is only a tiny percentage of lupus patients. Sometimes other labs or procedures can be helpful. Speak to your doctor.
Dr. Larry Greenbaum
Dr. Larry Greenbaum
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