Which medication is believed by experts to be more effective for heartburn and acid reflux: Prilosec OTC bid or protonix (pantoprazole) 40 mg bid?

Dose dependency. The class of drugs known as ppi's (proton pump inhibitors) has expanded considerably since Prilosec became available in 1989, & now includes: prilosec, prevacid, aciphex, protonix, zegerid, dexilant, (dexlansoprazole) nexium, as well as generic equivalents. All of these, with minor variation, block acid production at the proton-pump cellular level. Drug half-life & dose roughly determine duration & efficacy.

Related Questions

Acid reflux and heartburn. Price not an issue. A. Prilosec OTC bid or b. Protonix (pantoprazole) 40 mg bid? Please choose a or b.

Your choice. Proton pump inhibitor options expanded considerably since Prilosec became available in 1989 & now includes: prilosec, prevacid, aciphex, protonix, zegerid, dexilant, (dexlansoprazole) nexium, as well as generic equivalents. All, with minor variation, block acid production at the proton-pump cellular level. Drug half-life & dose roughly determine duration & efficacy. Tolerance is also an individual consideration. Read more...

Will Prilosec OTC help with my occasional heartburn/acid reflux?

Prilosec. Prilosec and similar medications tend to be better at preventing acid reflux than in treating it once it has already started. If you have only occasional heartburn, often the best treatment is good old-fashioned chewable antacids, such as Mylanta or Tums (calcium carbonate). If it is frequent, Prilosec might be helpful, but if it doesn't go away, you should see your doctor. Look up anti-reflux measures. Good luck. Read more...

Gerd not responding to Prilosec or protonix (pantoprazole).....Burning in chest, back throat. Could this be something else? Will I ever be able to get off a ppi?

Hopefully. If you are significantly overwight, your chances of getting off ppi drugs will be helped by weight loss and multiple small meals rather than a couple of large ones. Avoidance of alcohol, tobacco, caffeine, and anticholinergic drugs can help too. Read more...

I'm having acid reflux issues. I stopped taking protonix (pantoprazole) because it wasn't working. Should I go to the dr to get a new RX give myself time or get OTC?

Try another otc. The majority of the traditional reflux medications today are available over the counter. It's debatable that there is one proton-pump inhibitor better than the other (the meds we often use to treat reflux), however in my hospital we often used Nexium (esomeprazole) to good effect. It may be a factor of trying what is right for you. You could alternately try H2 blockers like ranitidine. Read more...