2 doctors weighed in:

What systems of the body are affected by Parkinson's disease?

2 doctors weighed in

In brief: Disease of misfolded

Proteins, affecting numerous neurotransmitters, especially a Dopamine deficit.
Main brain systems include basal ganglia (especially substantial nigra), but also dorsal vagal nucleus, locus ceruleous, and pallidum. But we are now finding areas of pathology in the gut (meissner's plexus), so this may be more systemic than we used to think.

In brief: Disease of misfolded

Proteins, affecting numerous neurotransmitters, especially a Dopamine deficit.
Main brain systems include basal ganglia (especially substantial nigra), but also dorsal vagal nucleus, locus ceruleous, and pallidum. But we are now finding areas of pathology in the gut (meissner's plexus), so this may be more systemic than we used to think.
Dr. Bennett Machanic
Dr. Bennett Machanic
Thank
1 comment
Dr. Gregg Friedman
Gregg L. Friedman MD Psychiatrist agrees
Get help from a real doctor now
Dr. Bennett Machanic
Board Certified, Neurology
48 years in practice
55M people helped
Continue
108,000 doctors available
Read more answers from doctors