Benefits of the selective beta blocker toprol (metoprolol) for heart failure/ cardiomyopathy?

Reverses Ht Failure. Toprol xl (specifically that formulation, not metoprolol tartrate) and Carvedilol (generic or Coreg (carvedilol) brand name) have been shown in large, well controlled clinical trials to slow and sometimes reverse the damage of heart failure. They operate by blocking a malfunctioning feedback loop of hormones and signaling molecules, ultimately by blocking the effect of adrenaline on the heart. Good question!

Related Questions

I take a beta-blocker med call metoprolol 75 mg day. My heart rate is still fast and my heart is pounding in my chest really hard all the time. Is it normal?

Yes. And by yes, I mean that there is still room for your prescriber to increase your dose. It's worth letting them know now that you have not gotten relief; you reach a steady concentration of metoprolol within your first doses, so if this dose is not effective enough, we already know. What's more, if you're on it partly to prevent arrhythmia, then we need to get that heart rate under control! Read more...

Why beta blockers is used in heart failure?

Remodeling. In chronic systolic dysfunction there is excessive elevation in serum catecholamines. This is due to activation of sympathetic nervous system. Excessive catecholamines cause apoptosis or programmed turning off of beta 1 receptor sites in heart. This results in pathological remodeling w heart getting more dilated and weaker. Beta blockers (carvedilol in particular) reset receptor responsiveness. Read more...
Beta blocker. Coreg (carvedilol) (carvidiol) is excellent for patient with heart failure. Long acting toprol xl (metoprolol) is another choice. Usually this is combined with "ace inhibitors" and water pills. Read more...

What is the therapeutic effect of beta blockers for heart failure?

Several. slowing of the heart rate allows longer filling time in diastole for the heart to pump a larger volume of blood with the next heart beat. Also, as blood pressure lowering agent lower resistance for the heart to pump against improves efficiency of the "failing" heart. Read more...