How to treat oily enlarged nose with acne?

Doxycycline. Retin-a (get the generic- tretinoin) will be useful. Note that it may at first be irritating and that it takes 3months to see the best result. Oral Doxycycline at 50- 100 mg a day will probably be required. You may have rosacea.
Retin-A. Retin-a can help. Its not he only thing, but it may improve your skin. Consult an experienced plastic surgeon or dermatologist.

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What can I do about an oily enlarged nose with acne?

Oily nosey. The simplest thing to do is keep it clean and dry. Surgery can address the size but this wouldn't affect the "oiliness" much. Read more...