How does exchange transfusion benefit sickle cell patients?

Removes sickle cells. Acute red cell exchange is useful in acute infarctive stroke, in acute chest and multi-organ failure syndromes. The process replaces sickled red blood cells with normal red blood cells. This procedure can also benefit certain patients on chronic transfusion plans by replacing sickled cells without increasing the viscosity of blood.

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Why would they do exchange transfusion in sickle cell patients?

Exchange transfusion. Sickled cells can cause dangerous complications such as stroke, multiorgan failure syndrome, acute chest syndrome, hepatic sequestration crisis, and priapism. Exchange transfusions remove the patient's sickled blood and replace it with normal blood, reversing or lessening the effects of the aforementioned complications and allowing restoration of normal organ function. Read more...