3 doctors weighed in:

I was prescribed 50, 000 iu of vitamin d2 for deficiency. Is this safe? I read something about high doses can cause hardening of the organs and death?

3 doctors weighed in
Dr. William Cromwell
Clinical Lipidology
2 doctors agree

In brief: Big dose less effect

Many physicians prefer a daily dose of 5, 000-8, 000 iu of vitamin d3.
A once weekly dose of 50, 000 iu is safe, but not as helpful due to poor absorption of a single dose of 50, 000 iu. Once 25 hydroxy vitamin d levels reach 60 - 80, the daily dose (5, 000-8, 000 iu) is usually cut in half and the patient followed to ensure the new dose is able to maintain therapeutic vitamin d levels.

In brief: Big dose less effect

Many physicians prefer a daily dose of 5, 000-8, 000 iu of vitamin d3.
A once weekly dose of 50, 000 iu is safe, but not as helpful due to poor absorption of a single dose of 50, 000 iu. Once 25 hydroxy vitamin d levels reach 60 - 80, the daily dose (5, 000-8, 000 iu) is usually cut in half and the patient followed to ensure the new dose is able to maintain therapeutic vitamin d levels.
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