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If the man has the sicklecell trait, do that mean all his children will have the trait too?

1 doctor weighed in

In brief: No

Sickle cell trait means that one is a "carrier" of the sickle cell gene.
It takes two copies of the sickle cell gene to manifest sickle cell disease. If a man has sickle cell trait, he may pass the sickle cell gene or the normal gene to his offspring - meaning 50% risk that he will pass on the sickle cell gene. The offspring's chance of inheritance also depends on the status of the mother!

In brief: No

Sickle cell trait means that one is a "carrier" of the sickle cell gene.
It takes two copies of the sickle cell gene to manifest sickle cell disease. If a man has sickle cell trait, he may pass the sickle cell gene or the normal gene to his offspring - meaning 50% risk that he will pass on the sickle cell gene. The offspring's chance of inheritance also depends on the status of the mother!
Dr. John Tillett
Dr. John Tillett
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