7 doctors weighed in:
Is long term use of omeprazole dangerous?
7 doctors weighed in

Emily Lu
Family Medicine
3 doctors agree
In brief: Yes
It is not recommended to take Omeprazole for longer than four months at a time.
Long-term use can lead to weakening of the stomach lining and increased risk of wrist, hip or spine fracture.

In brief: Yes
It is not recommended to take Omeprazole for longer than four months at a time.
Long-term use can lead to weakening of the stomach lining and increased risk of wrist, hip or spine fracture.
Emily Lu
Emily Lu
Answer assisted by Emily Lu, Medical Student
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Dr. Robert Kwok
Pediatrics
1 doctor agrees
In brief: Some side effects
Researchers are studying long term effects of Omeprazole (prilosec) use, because the drug is commonly used and works well in blocking stomach acid.
Long term use may lower absorption of calcium, vitamin b12, etc... Older folks may have a higher risk of hip fractures. Stomach acid kills germs, so some infections (such as c. Diff. Diarrhea) may be more likely in a person with suppressed acid.

In brief: Some side effects
Researchers are studying long term effects of Omeprazole (prilosec) use, because the drug is commonly used and works well in blocking stomach acid.
Long term use may lower absorption of calcium, vitamin b12, etc... Older folks may have a higher risk of hip fractures. Stomach acid kills germs, so some infections (such as c. Diff. Diarrhea) may be more likely in a person with suppressed acid.
Dr. Robert Kwok
Dr. Robert Kwok
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Dr. Satinder Aggarwal
Internal Medicine
1 doctor agrees
In brief: NO
When ppi were initially introduced there were concerns for long term use of omeprazole.
After many year of Omeprazole use we have seen any significant side effects.

In brief: NO
When ppi were initially introduced there were concerns for long term use of omeprazole.
After many year of Omeprazole use we have seen any significant side effects.
Dr. Satinder Aggarwal
Dr. Satinder Aggarwal
Thank
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