2 doctors weighed in:

Which medicine (10 mg of pravachol (pravastatin) or 10 mg simvastatin) is safer and tolerated while taking 5 mg of amlodipine (ccb) at night.Thanks?

2 doctors weighed in
Dr. George Mathew
Internal Medicine - Cardiology

In brief: Pravastatin

Pravastatin may be more tolerable and safer than simva because of drug to drug interactions!

In brief: Pravastatin

Pravastatin may be more tolerable and safer than simva because of drug to drug interactions!
Dr. George Mathew
Dr. George Mathew
Thank
Dr. Robert Binford
Surgery - Thoracic

In brief: Pravostatin maybe

There is an interaction between amlodipine and statin drugs which can cause a breakdown in muscle tissues.
It is more common with Simvastatin than pravachol (pravastatin). The recommendations say Simvastatin dose should be 20mg or less if taking amlodipine. So both of your choices are ok. But assume risk slightly higher with simvastatin. Note Simvastatin maybe more effective in lowering cholesterol.

In brief: Pravostatin maybe

There is an interaction between amlodipine and statin drugs which can cause a breakdown in muscle tissues.
It is more common with Simvastatin than pravachol (pravastatin). The recommendations say Simvastatin dose should be 20mg or less if taking amlodipine. So both of your choices are ok. But assume risk slightly higher with simvastatin. Note Simvastatin maybe more effective in lowering cholesterol.
Dr. Robert Binford
Dr. Robert Binford
Thank
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