6 doctors weighed in:
How safe and effective is 50mg of Benadryl (diphenhydramine) for sleep? 
6 doctors weighed in

Dr. Paul Carter
Internal Medicine - Allergy & Immunology
2 doctors agree
In brief: Very
Diphenhydramine is the active ingredient in bendryl, and is also used on multiple other bedtime over the counter preparations to cause drowsiness - i.
e., tylenol (acetaminophen) pm, simply sleep, etc.

In brief: Very
Diphenhydramine is the active ingredient in bendryl, and is also used on multiple other bedtime over the counter preparations to cause drowsiness - i.
e., tylenol (acetaminophen) pm, simply sleep, etc.
Dr. Paul Carter
Dr. Paul Carter
Thank
Dr. Christopher Powers
Obstetrics & Gynecology
2 doctors agree
In brief: Safe, not effective
Will help put you to sleep, but won't keep you asleep and you'll likely awake with a hung-over feeling.
Moreover, it is constipating if used persistently. I prefer Ambien or Lunesta (eszopiclone) in my patients, unless there pregnant. If so, Benadryl or doxylamine, are my only choices.

In brief: Safe, not effective
Will help put you to sleep, but won't keep you asleep and you'll likely awake with a hung-over feeling.
Moreover, it is constipating if used persistently. I prefer Ambien or Lunesta (eszopiclone) in my patients, unless there pregnant. If so, Benadryl or doxylamine, are my only choices.
Dr. Christopher Powers
Dr. Christopher Powers
Thank
Get help from a real doctor now
Dr. Vicken Poochikian
Board Certified,
38 years in practice
2M people helped
Continue
107,000 doctors available
Read more answers from doctors