2 doctors weighed in:

Could you have high total T4 levels but have normal free T4 levels?

2 doctors weighed in
Dr. David Geffner
Internal Medicine - Endocrinology
1 doctor agrees

In brief: Yes

Total T4 reflects T4 bound to proteins in your blood.
Free T4 measures the amount of T4 that is free and not bound so that it can be metabolically active. Thus women taking Estrogens (as in bc pills) have elevated levels of thyroid binding globulin and elevated total t4, but normal free t4.

In brief: Yes

Total T4 reflects T4 bound to proteins in your blood.
Free T4 measures the amount of T4 that is free and not bound so that it can be metabolically active. Thus women taking Estrogens (as in bc pills) have elevated levels of thyroid binding globulin and elevated total t4, but normal free t4.
Dr. David Geffner
Dr. David Geffner
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