Yes. Paracetamol or Acetaminophen (tylenol (acetaminophen)) is a completely different class of drug than Ibuprofen (advil, motrin) - nsaids - non-steroidal anti-inflammatory drugs. Paracetamol is the common generic name for tylenol (acetaminophen) outside the us. Paracetetamol is metabolized in the liver and the main risk is liver toxicity. It can be taken with Ibuprofen or other nsaids.