5 doctors weighed in:

What is msi test in colon cancer?

5 doctors weighed in
Dr. Joseph Sucher
Surgery - Trauma
2 doctors agree

In brief: Screening tool

Msi test has a few uses in colorectal cancer screening and surveillance.
While only 15 percent of colorectal cancers are msi positive, as many as 90 percent of patients with lynch syndrome (specific genetic etiology for colorectal cancer) have a positive msi test. The test may also be helpful in determining those patients with stage ii or iii cancer who may benefit from chemotherapy.

In brief: Screening tool

Msi test has a few uses in colorectal cancer screening and surveillance.
While only 15 percent of colorectal cancers are msi positive, as many as 90 percent of patients with lynch syndrome (specific genetic etiology for colorectal cancer) have a positive msi test. The test may also be helpful in determining those patients with stage ii or iii cancer who may benefit from chemotherapy.
Dr. Joseph Sucher
Dr. Joseph Sucher
Thank
1 doctor agrees

In brief: A genetic test

Cancers develops when the repair mechanisms fails, ( mismatch in repair systems ) high micro satellite instability as seen in genetic disease like lynch syndrome who develop colon cancers then msi - h (high) complex science i hope explained to you in a simple terms

In brief: A genetic test

Cancers develops when the repair mechanisms fails, ( mismatch in repair systems ) high micro satellite instability as seen in genetic disease like lynch syndrome who develop colon cancers then msi - h (high) complex science i hope explained to you in a simple terms
Dr. Addagada Rao
Dr. Addagada Rao
Thank
Dr. Joseph Woods
Pathology

In brief: Microsatellite,,,

Msi stands for microsatellite instability.
An msi test tests for this in samples of dna from cells. Microsatellites are nucleotide repeats, like ca repeats normally seen in dna, but only up to cerrtain lengths, and occur many times in the dna sequence. However, if these are longer or shorter, this is termed microsatellite instability, and is seen in cancerous cells, like colorectal cancer.

In brief: Microsatellite,,,

Msi stands for microsatellite instability.
An msi test tests for this in samples of dna from cells. Microsatellites are nucleotide repeats, like ca repeats normally seen in dna, but only up to cerrtain lengths, and occur many times in the dna sequence. However, if these are longer or shorter, this is termed microsatellite instability, and is seen in cancerous cells, like colorectal cancer.
Dr. Joseph Woods
Dr. Joseph Woods
Thank
Get help from a real doctor now
Dr. Mark Pack
Board Certified, Surgery
28 years in practice
3M people helped
Continue
111,000 doctors available
Read more answers from doctors