1 doctor weighed in:

Do liver dysfunction increase or decrease the bun level?

1 doctor weighed in
Dr. John Fung
Surgery

In brief: Depends

Bun, or blood urea nitrogen, is the byproduct of normal protein breakdown and conversion to urea by the liver. BUN is excreted by the kidney.
So BUN can be up or down depending on the synthesis by the liver or excretion by the kidney. In sudden liver failure, e.g. Acute liver failure, BUN is low, since urea synthesis by the liver is reduced, but if the kidneys do not work, BUN will go up.

In brief: Depends

Bun, or blood urea nitrogen, is the byproduct of normal protein breakdown and conversion to urea by the liver. BUN is excreted by the kidney.
So BUN can be up or down depending on the synthesis by the liver or excretion by the kidney. In sudden liver failure, e.g. Acute liver failure, BUN is low, since urea synthesis by the liver is reduced, but if the kidneys do not work, BUN will go up.
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