No, not necessarily
In a typical 43 year old, there are changes that occur that could be considered "peri-menopausal changes".
These might include:
1. Changes in cycle regularity (related to irregularity in ovulation
2. Hot flashes
3. Changes in hair (decreased number and caliber)
4. Vaginal dryness
5. Pain with intercourse (related to #4)
these changes can begin in your late 30's to 40's.