19 doctors weighed in:
Is there any risk of allergic reaction with collagen fillers? How do I find out if i’m allergic?
19 doctors weighed in

Dr. Andrew Murphy
Internal Medicine - Allergy & Immunology
5 doctors agree
In brief: Possible
As a general rule we are at risk for allergic reactions to anything we ingest or inject into our bodies.
The question becomes whether one is at higher risk than the general population. Before you inject or ingest anything new speak with your physician to assess the risk.

In brief: Possible
As a general rule we are at risk for allergic reactions to anything we ingest or inject into our bodies.
The question becomes whether one is at higher risk than the general population. Before you inject or ingest anything new speak with your physician to assess the risk.
Dr. Andrew Murphy
Dr. Andrew Murphy
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Dr. Otto Placik
Surgery - Plastics
3 doctors agree
In brief: Yes
It is nearly impossible with human skin and therefore this can be used without skin testing.
Recent forms of porcine collagen such as evolence did not require testing either. However prior forms of bovine collagen did require skin testing to diminish the risk for an unknown collagen allergic reaction.

In brief: Yes
It is nearly impossible with human skin and therefore this can be used without skin testing.
Recent forms of porcine collagen such as evolence did not require testing either. However prior forms of bovine collagen did require skin testing to diminish the risk for an unknown collagen allergic reaction.
Dr. Otto Placik
Dr. Otto Placik
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Dr. Jeffrey Pollard
ENT - Head & Neck Surgery
2 doctors agree
In brief: Skin Test Needed
Collagen fillers are rarely used anymore because of the short duration of correction and the risk of allergic reactions.
A skin test is needed with the same product that is planning to be used (as collagen can come from a variety of sources), and should be tested at least 2-4 weeks before the treatment to ensure no reaction. Best advice is to go with a longer lasting, safer filler such as juvederm.

In brief: Skin Test Needed
Collagen fillers are rarely used anymore because of the short duration of correction and the risk of allergic reactions.
A skin test is needed with the same product that is planning to be used (as collagen can come from a variety of sources), and should be tested at least 2-4 weeks before the treatment to ensure no reaction. Best advice is to go with a longer lasting, safer filler such as juvederm.
Dr. Jeffrey Pollard
Dr. Jeffrey Pollard
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Dr. John Hoffmann
Surgery - Plastics
1 doctor agrees
In brief: Very high risk
About one third of people will have an allergic reaction to collagen fillers.
These are no longer marketed in the usa and have largely been replaced by the much safer and longer lasting ha fillers such as Restylane (dermal fillers) or juvederm.

In brief: Very high risk
About one third of people will have an allergic reaction to collagen fillers.
These are no longer marketed in the usa and have largely been replaced by the much safer and longer lasting ha fillers such as Restylane (dermal fillers) or juvederm.
Dr. John Hoffmann
Dr. John Hoffmann
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Dr. Ronald Shelton
Dermatology
1 doctor agrees
In brief: Allergy rare filler
Collagen injections are no longer done.
We used to do two skin tests and if they were both negative, the patient would have a 1.5 % chance of developing a red bump for months as an allergic reaction to the cow hide collagen. Currently, Restylane (dermal fillers) and juvederm hyaluronic acids are almost unheard of as causing allergic reactions. No skin test is required.

In brief: Allergy rare filler
Collagen injections are no longer done.
We used to do two skin tests and if they were both negative, the patient would have a 1.5 % chance of developing a red bump for months as an allergic reaction to the cow hide collagen. Currently, Restylane (dermal fillers) and juvederm hyaluronic acids are almost unheard of as causing allergic reactions. No skin test is required.
Dr. Ronald Shelton
Dr. Ronald Shelton
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Dr. Mike Bowman
ENT - Head & Neck Surgery
1 doctor agrees
In brief: Sculptra is safe
Older style collagen fillers indeed had high risk of allergic reactions and required the use of a test injection.
Sculptra is a newer product which helps your body build its own collagen. Like all medicines, there is a very small risk of an allergic reaction, but this is extremely rare. Other fillers like juvederm and other ha fillers also have a very low risk of reactions. Best wishes.

In brief: Sculptra is safe
Older style collagen fillers indeed had high risk of allergic reactions and required the use of a test injection.
Sculptra is a newer product which helps your body build its own collagen. Like all medicines, there is a very small risk of an allergic reaction, but this is extremely rare. Other fillers like juvederm and other ha fillers also have a very low risk of reactions. Best wishes.
Dr. Mike Bowman
Dr. Mike Bowman
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Dr. H. William Song
Aesthetic Medicine
1 doctor agrees
In brief: Yes
Collagen fillers do not last very long and have a significant risk of allergic reactions.
Hyaluronic acid and calcium based fillers like juvederm and Radiesse have pretty much replaced collagen as the treatment of choice for dermal fillers.

In brief: Yes
Collagen fillers do not last very long and have a significant risk of allergic reactions.
Hyaluronic acid and calcium based fillers like juvederm and Radiesse have pretty much replaced collagen as the treatment of choice for dermal fillers.
Dr. H. William Song
Dr. H. William Song
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Dr. Darab Hormozi
Surgery - Plastics
In brief: Yes there is rsk
Collagen allergy is not uncommun and is detected with a skin test.
Most surgeons at present use fillers like juvederm and radiess with better result and less side effect. The mozt advanced " filler" is to use your own stem cells. With stem cells , there is no reaction, allergy or rejection. It is safe and long lasting. It is performed under local anesthesia.

In brief: Yes there is rsk
Collagen allergy is not uncommun and is detected with a skin test.
Most surgeons at present use fillers like juvederm and radiess with better result and less side effect. The mozt advanced " filler" is to use your own stem cells. With stem cells , there is no reaction, allergy or rejection. It is safe and long lasting. It is performed under local anesthesia.
Dr. Darab Hormozi
Dr. Darab Hormozi
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Dr. Andre Berger
Cosmetic Surgery
In brief: Yes
Collagen fillers are derived from animal sources such as cows and require skin testing to determine if there may be an allergy.
To test, a tiny amount of filler is injected under the skin to observe any possible reaction, such as redness, swelling or itching. If there is an allergic reaction, alternative materials can be considered, such as other synthetic non-collagen fillers or fat transfer.

In brief: Yes
Collagen fillers are derived from animal sources such as cows and require skin testing to determine if there may be an allergy.
To test, a tiny amount of filler is injected under the skin to observe any possible reaction, such as redness, swelling or itching. If there is an allergic reaction, alternative materials can be considered, such as other synthetic non-collagen fillers or fat transfer.
Dr. Andre Berger
Dr. Andre Berger
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