Can a low dose (5mg) of prednisone (prescribed to reduce mild adrenal hyperplasia to improve female fertility) aggravate my depression?

Yes it can

Open-uri20121202-22868-1j6ot8g
Yes, prednisone can aggravate depression. Please discuss this with your physicians. Dose adjustments may be needed in your prednisone, your antidepressants, or both. If feeling depressed but not yet being treated for depression, an evaluation could help discern what's going on. Effective treatment could be provided.
Sign Up

Get personalized answers from doctors!

Deltasone Depression Fertility Hopelessness Liquid pred Melancholia Prednisone Women Female Child health

Could, but unlikely!

Open-uri20130717-22550-cgjqsz
You will need to discuss this with your doctor. Since you were found to have low levels of cortisol, itself, which can causes depression (Was this measured or simply guessed at?), This is a low dose, and would likely suppress your own cortisol production even further! So the net rise in steroid activity is small.Could happen, but I am on the side of unlikely and that it might be a coincidence!
Sign Up

Get personalized answers from doctors!

Child health Cortisol level Deltasone Depression Female Fertility Liquid pred Prednisone Women

Maybe

Prednisone
It would not be common at this low dose, but it is not impossible.
Sign Up

Get personalized answers from doctors!

Deltasone Depression Fertility Liquid pred Prednisone Women Female Child health