Unlikely. Patients may endorse neuropathic type symptoms when initiating or getting of this class of medication, known as ssris. Particularly, if a high dose is started without gradual titration or if a higher dose is stopped abruptly. I've seen it occur even in the setting of proper titration or weaning. This side effect is self limited and should resolve in its own. The time course is quite variable.
How does Prozac (fluoxetine) reduce pain? Helps with my back pain/my neuropathy in my foot. Doesn't seem to help all pain (fibromyalgia = not as much help)
Chemicals. Prozac (fluoxetine) is approved for chronic headaches but otherwise lacks indication for chronic pain such as neuropathy. It may help improving the pain by improving underlying depression, even if it was subtle or undiagnosed. Improvements in depression are linked to heightened pain tolerance. Read more...