6 doctors weighed in:

Is sickle cell anemia hereditary?

6 doctors weighed in
Dr. Richard Roberts
Clinical Genetics
2 doctors agree

In brief: Yes.

it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation.
If they are, the chance of each child being affected is 1 in 4.

In brief: Yes.

it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation.
If they are, the chance of each child being affected is 1 in 4.
Dr. Richard Roberts
Dr. Richard Roberts
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Dr. Ankush Bansal
Internal Medicine
1 doctor agrees

In brief: Yes

Sickle cell anemia is due to a genetic mutation in the dna that encodes for the hemoglobin molecule.
Thus, it is hereditary.

In brief: Yes

Sickle cell anemia is due to a genetic mutation in the dna that encodes for the hemoglobin molecule.
Thus, it is hereditary.
Dr. Ankush Bansal
Dr. Ankush Bansal
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Dr. Scott Diede
Pediatrics - Hematology & Oncology

In brief: Sickle cell disease

Yes. For example, if both parents have sickle cell trait (each have one copy of a sickle beta-hemoglobin gene and one unaffected copy), they have a 25% chance of having a child with sickle cell disease, a 50% chance of the child having sickle cell trait, and a 25% chance of the child having completely normal hemoglobin (no trait or sickle cell disease).

In brief: Sickle cell disease

Yes. For example, if both parents have sickle cell trait (each have one copy of a sickle beta-hemoglobin gene and one unaffected copy), they have a 25% chance of having a child with sickle cell disease, a 50% chance of the child having sickle cell trait, and a 25% chance of the child having completely normal hemoglobin (no trait or sickle cell disease).
Dr. Scott Diede
Dr. Scott Diede
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