8 doctors weighed in:
Does Down syndrome increase your risk for leukemia?
8 doctors weighed in

Dr. Ankush Bansal
Internal Medicine
5 doctors agree
In brief: Yes
Down syndrome unfortunately leads to an increased risk of acute myeloid (especially megakaryocytic) and acute lymphocytic leukemias.
The risk of acute leukemia in the first 5 years of life is 56x higher than non-downs kids and overall, 1 in 150 downs patients develop leukemia.

In brief: Yes
Down syndrome unfortunately leads to an increased risk of acute myeloid (especially megakaryocytic) and acute lymphocytic leukemias.
The risk of acute leukemia in the first 5 years of life is 56x higher than non-downs kids and overall, 1 in 150 downs patients develop leukemia.
Dr. Ankush Bansal
Dr. Ankush Bansal
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1 comment
Dr. Scott Diede
In addition, to look on the bright side of things, the cure rates for children with Trisomy 21 and leukemia are higher than the general population.
Dr. William Singer
Pediatrics - Neurology
In brief: Yes
Acute lymphoblastic leukemia is 20 times more common than the general population.
There is an abnormality in a protein PRC-2 which contributes to the development of ALL.

In brief: Yes
Acute lymphoblastic leukemia is 20 times more common than the general population.
There is an abnormality in a protein PRC-2 which contributes to the development of ALL.
Dr. William Singer
Dr. William Singer
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Dr. Osman Farooq
Pediatrics - Neurology
In brief: Yes
Cancers of the blood, such as leukemia, are more common in people who have down's syndrome.
Specifically, acute lymphoblastic leukemia (all) is 10 times more common, and acute myelogenous leukemia (AML) is 50 times m ore common.

In brief: Yes
Cancers of the blood, such as leukemia, are more common in people who have down's syndrome.
Specifically, acute lymphoblastic leukemia (all) is 10 times more common, and acute myelogenous leukemia (AML) is 50 times m ore common.
Dr. Osman Farooq
Dr. Osman Farooq
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