2 doctors weighed in:
Could taking naltrexone help with fibromyalgia?
2 doctors weighed in

Dr. Einar Ottestad
Pain Management
In brief: Yes
Low dose Naltrexone works well for fibromyalgia.
Taper all opioid medications. Wait a few weeks. Start at 4.5 mg taken 2 hours before bedtime. After about 2-3 weeks sleep improves. After about a month pain scores start dropping. Very safe, essentially no side effects. Some people do have vivid dreams.

In brief: Yes
Low dose Naltrexone works well for fibromyalgia.
Taper all opioid medications. Wait a few weeks. Start at 4.5 mg taken 2 hours before bedtime. After about 2-3 weeks sleep improves. After about a month pain scores start dropping. Very safe, essentially no side effects. Some people do have vivid dreams.
Dr. Einar Ottestad
Dr. Einar Ottestad
Thank
Dr. Betty Keller
Internal Medicine - Rheumatology
In brief: Possibly
One small (10 subjects) uncontrolled trial using low dose Naltrexone (ldn) for fibromyalgia showed some promise.
The study showed that 7 out of 10 study subjects with fibromyalgia had a 30% reduction in pain. Additional studies need to be done to see if it is really effective. The drug cannot be used if the patient is on opioid pain medications. Discuss with your doctor.

In brief: Possibly
One small (10 subjects) uncontrolled trial using low dose Naltrexone (ldn) for fibromyalgia showed some promise.
The study showed that 7 out of 10 study subjects with fibromyalgia had a 30% reduction in pain. Additional studies need to be done to see if it is really effective. The drug cannot be used if the patient is on opioid pain medications. Discuss with your doctor.
Dr. Betty Keller
Dr. Betty Keller
Thank
Get help from a real doctor now
Dr. Jane Van Dis
Board Certified, Obstetrics & Gynecology
14 years in practice
47M people helped
Continue
108,000 doctors available
Read more answers from doctors