Can you combine taking cymbalta (duloxetine) and naltrexone for depression?

Probably. Cymbalta (duloxetine) for depression is fine. I find no indication for the use of Naltrexone in depression. If you are referring to just having to use the two at the same time, i find no contraindication for using the two together, ie, no drug to drug interaction. Both drugs are for serious illness and make shure you thoroughly discuss this with your pcp, addiction md, other provider or pharmacist/pharmd.
Yes. There is no contraindications to that combination.
Naltrexone. The only literature of which I am aware of Naltrexone being used to decrease depression would be the theory of low dose naltrexone.There is some evidence that low-dose Naltrexone (ldn) can upregulate endogenous opioid activity and  may have a role in promoting stress resilience, exercise, social bonding, and emotional well-being, as well as amelioration of psychiatric problems such as depression.

Related Questions

Are there any long term health consequences for taking Cymbalta (duloxetine) long term? I have been on it for 7+ years for depression. Currently 30 mg.

No. Cymbalta (duloxetine) is safe taken long term for depression. You will need to taper off if you ever decide to have a trial off of it. Read more...
Not really. You need a regular physical yearly and when you take any medications long-term, your doctor usually checks your metabolic profile, complete blood count, and general profile to rule out any illnesses and any unusual findings will be monitored. In addition, your dose is low and may just be a maintenance dose. You may want to discuss further with your doctor. Read more...

Is 30 mg of Cymbalta (duloxetine) low to combat depression/anxiety?

Cymbalta (duloxetine) Yes that is the usual starting dose. Read more...
Probably not. While 30 mg once or twice a day is a usual starting dose, it is often insufficient to treat anxiety or depression. People generally require 60 to 120 mg per day. Read more...
Yes. The 30 mg dose is typically an introductory strength to try to prevent the nausea side effects that can be experienced with higher doses. The more effective levels are at 90-120 mg daily, but have seen some value even in the 30 mg area. Would next try 60 mg and see how you do. Read more...