5 doctors weighed in:
Will Narcan (naloxone) reverse an opiate overdose once cardiac arrest has occurred?
5 doctors weighed in

Dr. Michael DePietro
Internal Medicine - Pulmonary Critical Care
3 doctors agree
In brief: Not completely
Narcan (naloxone) can reverse a narcotic overdose to a point.
If someone takes a narcotic overdose, and it is enough to stop breathing, the lack of oxygen and rise in carbon dioxide can cause the heart to stop ( cardiac arrest) at that point simply reversing the effect of the narcotic that started the process is not enough, one take additional measures to restore a pulse and resuscitate the patient.

In brief: Not completely
Narcan (naloxone) can reverse a narcotic overdose to a point.
If someone takes a narcotic overdose, and it is enough to stop breathing, the lack of oxygen and rise in carbon dioxide can cause the heart to stop ( cardiac arrest) at that point simply reversing the effect of the narcotic that started the process is not enough, one take additional measures to restore a pulse and resuscitate the patient.
Dr. Michael DePietro
Dr. Michael DePietro
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Dr. Joseph De santi
Family Medicine
In brief: Arresting Narcan (naloxone)
It depends entirely on the method of delivery and the interval circulation during the arrest.
The medication will certainly do its pharmacologic action as long as circulation is restored to some extent. The onset of action may be delayed but the drug efficacy should be unaffected once administered. As with all drugs administered during an arrest their efficacy is diminished to some extent.

In brief: Arresting Narcan (naloxone)
It depends entirely on the method of delivery and the interval circulation during the arrest.
The medication will certainly do its pharmacologic action as long as circulation is restored to some extent. The onset of action may be delayed but the drug efficacy should be unaffected once administered. As with all drugs administered during an arrest their efficacy is diminished to some extent.
Dr. Joseph De santi
Dr. Joseph De santi
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