6 doctors weighed in:
How does cocaine actually effect the brain?
6 doctors weighed in

Dr. Joseph De santi
Family Medicine
3 doctors agree
In brief: Cocaine on the Brain
This is a complex answer to address here, but in summary it works on specific receptors in certain areas of the brain responsible for pleasure.
As a result, this highly addictive sensation is then craved psychologically while at the same time your body will physically depend on the substance being present to feel "normal" when in fact you're in a heightened sense of stimulation and arousal.

In brief: Cocaine on the Brain
This is a complex answer to address here, but in summary it works on specific receptors in certain areas of the brain responsible for pleasure.
As a result, this highly addictive sensation is then craved psychologically while at the same time your body will physically depend on the substance being present to feel "normal" when in fact you're in a heightened sense of stimulation and arousal.
Dr. Joseph De santi
Dr. Joseph De santi
Thank
1 comment
Dr. Arthur Heller
Cocaine affects dopamine (neurotransmitter) in the brain; prolonged use depletes and affects brain's ability to make it. Cocaine can also cause stroke
Dr. Alan Wartenberg
Addiction Medicine
2 doctors agree
In brief: Dopamine
Dopamine is a chemical responsible for many things in the brain, including (in the limbic system) pleasure, euphoria and reward.
Cocaine releases Dopamine in large amounts from its storage sites. However, the more Cocaine you use, the less Dopamine you have, and you keep "chasing the dragon". It is a dangerous addiction. It also causes brain damage when used in high doses for long periods of time.

In brief: Dopamine
Dopamine is a chemical responsible for many things in the brain, including (in the limbic system) pleasure, euphoria and reward.
Cocaine releases Dopamine in large amounts from its storage sites. However, the more Cocaine you use, the less Dopamine you have, and you keep "chasing the dragon". It is a dangerous addiction. It also causes brain damage when used in high doses for long periods of time.
Dr. Alan Wartenberg
Dr. Alan Wartenberg
Thank
Get help from a real doctor now
Dr. Eric Weisman
Board Certified, Neurology
32 years in practice
9M people helped
Continue
108,000 doctors available
Read more answers from doctors