5 doctors weighed in:

Is one injection of epinephrine enough to treat an allergic reaction?

5 doctors weighed in
Dr. Manav Singla
Internal Medicine - Allergy & Immunology
2 doctors agree

In brief: Some need seconds

Some people may need a second injection of epinephrine, so always keep second Epipen handy or make sure you know how to use the second dose in your twinject.

In brief: Some need seconds

Some people may need a second injection of epinephrine, so always keep second Epipen handy or make sure you know how to use the second dose in your twinject.
Dr. Manav Singla
Dr. Manav Singla
Thank
1 comment
Dr. Monica Vasudev
The Epipen comes as a twin pack which is easy to administer.
Dr. Michael Zacharisen
Internal Medicine - Allergy & Immunology

In brief: Usually

About 25% of anaphylactic reactions will require a second dose of epi due to a dual or late phase reaction.
If the epi is given in a timely manner, the immediate reaction should improve. However, a second dose can be given 5-10 minutes later if necessary. In my allergy experience (19 years) i've rarely needed to give a second dose---anecdotal.

In brief: Usually

About 25% of anaphylactic reactions will require a second dose of epi due to a dual or late phase reaction.
If the epi is given in a timely manner, the immediate reaction should improve. However, a second dose can be given 5-10 minutes later if necessary. In my allergy experience (19 years) i've rarely needed to give a second dose---anecdotal.
Dr. Michael Zacharisen
Dr. Michael Zacharisen
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