3 doctors weighed in:
Is it safe to get dactinomycin while pregnant or breastfeeding?
3 doctors weighed in

Dr. Stephen Pappachen
Obstetrics & Gynecology
1 doctor agrees
In brief: No
This is considered a category d (fda classification) medication in pregnancy and "unsafe" for lactation purposes.
So, generally speaking, i would say avoid exposure to this medication during pregnancy and breastfeeding. However, as always, risks and benefits must be weighed here. Perinatology consultation may be appropriate, especially if there are overriding benefits to mom.

In brief: No
This is considered a category d (fda classification) medication in pregnancy and "unsafe" for lactation purposes.
So, generally speaking, i would say avoid exposure to this medication during pregnancy and breastfeeding. However, as always, risks and benefits must be weighed here. Perinatology consultation may be appropriate, especially if there are overriding benefits to mom.
Dr. Stephen Pappachen
Dr. Stephen Pappachen
Thank
Dr. Andrew Turrisi
Radiation Oncology
In brief: Actinomycin D is
A big molecule, so it may not cross placental barrier, but it is highly unlikely that it is safe to use in breast feeding, and clearly dubious to use if a patient is known to be pregnant.

In brief: Actinomycin D is
A big molecule, so it may not cross placental barrier, but it is highly unlikely that it is safe to use in breast feeding, and clearly dubious to use if a patient is known to be pregnant.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
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