6 doctors weighed in:
Does my child have to inherit the same exact mutation from both parents in order to develop cystic fibrosis?
6 doctors weighed in

Dr. Brian Bezack
Pediatrics - Pulmonology
3 doctors agree
In brief: No
You need 2 mutations to inherit cf, but they can be, and often are, 2 different mutations.
The type of mutation can have an impact on the severity of the disease and the child's prognosis.

In brief: No
You need 2 mutations to inherit cf, but they can be, and often are, 2 different mutations.
The type of mutation can have an impact on the severity of the disease and the child's prognosis.
Dr. Brian Bezack
Dr. Brian Bezack
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Dr. HARRY OPSIMOS
Pediatrics - Pulmonology
1 doctor agrees
In brief: No
Cystic fibrosis has been associated with over 1500 mutations.
A person does not need to have the exact same 2 mutations inherited to have the disease. A CF patient can have 2 different mutations inherited from the parents. The extent of the disease may depend on what mutations a person has, but also varies from one patient to another even with the same mutations. Other factors play a role as well.

In brief: No
Cystic fibrosis has been associated with over 1500 mutations.
A person does not need to have the exact same 2 mutations inherited to have the disease. A CF patient can have 2 different mutations inherited from the parents. The extent of the disease may depend on what mutations a person has, but also varies from one patient to another even with the same mutations. Other factors play a role as well.
Dr. HARRY OPSIMOS
Dr. HARRY OPSIMOS
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