6 doctors weighed in:

Can just one parent have sickle trait and the child inherit the total disease?

6 doctors weighed in
Dr. Joseph Torkildson
Pediatrics - Hematology & Oncology
2 doctors agree

In brief: Unlikely

A person is born with a genetic condition either because they inherit it or they experience what is called a "mutation".
Being born with sickle cell anemia means one has two hemoglobin genes with the same mutation. Spontaneous sickle mutations are thought to occur extremely rarely, so virtually all babies with ssa inherit an abnormal gene from both parents.

In brief: Unlikely

A person is born with a genetic condition either because they inherit it or they experience what is called a "mutation".
Being born with sickle cell anemia means one has two hemoglobin genes with the same mutation. Spontaneous sickle mutations are thought to occur extremely rarely, so virtually all babies with ssa inherit an abnormal gene from both parents.
Dr. Joseph Torkildson
Dr. Joseph Torkildson
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Dr. James Ferguson
Pediatrics
2 doctors agree

In brief: No

Trus sickle cell disease requires a recessive gene contribution from both parents.
There are other types of hemaglobin disorders that can pair up with a single sickle cell gene and reak havac, but true ss disease requires that both parents be carriers.

In brief: No

Trus sickle cell disease requires a recessive gene contribution from both parents.
There are other types of hemaglobin disorders that can pair up with a single sickle cell gene and reak havac, but true ss disease requires that both parents be carriers.
Dr. James Ferguson
Dr. James Ferguson
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