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What is the lifespan for a child have suffering from major thalassemia?

3 doctors weighed in
Dr. Robert Kwok
Pediatrics
1 doctor agrees

In brief: Beta: 20's to 30's

Alpha thalassemia major is fatal before birth in almost all cases.
Beta thalassemia major babies look normal at birth. Symptoms start after age 6-8 months. If good treatment starts then, with regular transfusions, plus chelation to remove excess iron, patients can survive into their 20's and 30's. Medical care and technologies improve over time, so that patients today may live longer than before.

In brief: Beta: 20's to 30's

Alpha thalassemia major is fatal before birth in almost all cases.
Beta thalassemia major babies look normal at birth. Symptoms start after age 6-8 months. If good treatment starts then, with regular transfusions, plus chelation to remove excess iron, patients can survive into their 20's and 30's. Medical care and technologies improve over time, so that patients today may live longer than before.
Dr. Robert Kwok
Dr. Robert Kwok
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1 comment
Dr. Scott Miller
Or maybe longer if compliance with chelation is good. Stem cell transpllant may be possible, and it seems gene therapy might finally be at hand.
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