6 doctors weighed in:
Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?
6 doctors weighed in

Dr. Martin Andreansky
Pediatrics - Hematology & Oncology
2 doctors agree
In brief: In theory 25%
Please remember these statistics apply to large population and therefore it is possible for a couple with sickle cell trait have children with and without sickle cell disease.

In brief: In theory 25%
Please remember these statistics apply to large population and therefore it is possible for a couple with sickle cell trait have children with and without sickle cell disease.
Dr. Martin Andreansky
Dr. Martin Andreansky
Thank
Dr. James Ferguson
Pediatrics
2 doctors agree
In brief: Simple math
Any conception of two sickle cell carriers could produce :sickle cell disease (1/4), carrier(2/4) normal(1/4).
It is important to stress, any pregnancy could produce ss sickle cell disease no mater if the previous pregnancy did or did not. Many state newborn screening programs look for ss or s trait. If baby gets a s gene from each parent they will get sick. Carriers generally do not.

In brief: Simple math
Any conception of two sickle cell carriers could produce :sickle cell disease (1/4), carrier(2/4) normal(1/4).
It is important to stress, any pregnancy could produce ss sickle cell disease no mater if the previous pregnancy did or did not. Many state newborn screening programs look for ss or s trait. If baby gets a s gene from each parent they will get sick. Carriers generally do not.
Dr. James Ferguson
Dr. James Ferguson
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