3 doctors weighed in:
Do both parents have to have the actual sickle cell trait in order for the child to have sickle disease sc?
3 doctors weighed in

Dr. James Ferguson
Pediatrics
1 doctor agrees
In brief: One has S/One has C
Parents have 2 genes at a given gene location in their dna.
They have a carrier state if one gene is normal and one abnormal.In sickle trait the pair is sn, in c trait the pair is cn. For a child to have sc (sickle c) they get the s from one and the c from the other. If one parent is sc and the other sn(sickle trait), you could have ss, sn or sc.

In brief: One has S/One has C
Parents have 2 genes at a given gene location in their dna.
They have a carrier state if one gene is normal and one abnormal.In sickle trait the pair is sn, in c trait the pair is cn. For a child to have sc (sickle c) they get the s from one and the c from the other. If one parent is sc and the other sn(sickle trait), you could have ss, sn or sc.
Dr. James Ferguson
Dr. James Ferguson
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Dr. James Marx
Pain Management
In brief: No Only One
One with the hb s trait, the other with hb c.
Hb c has very few symptoms in the absence of the hb s gene. Hb sc patients are more symptomatic than the hb c disease patients as the presence of the s trait gene worsens the effect of the usually mild hb c gene causing disease..

In brief: No Only One
One with the hb s trait, the other with hb c.
Hb c has very few symptoms in the absence of the hb s gene. Hb sc patients are more symptomatic than the hb c disease patients as the presence of the s trait gene worsens the effect of the usually mild hb c gene causing disease..
Dr. James Marx
Dr. James Marx
Thank
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