HDN. The process of hemolytic disease of the newborn (HDN) starts soon after birth, however the symptoms (mainly jaundice) may not be detected if clinicians do not maintain a high index of suspicion. HDN due to Rh incompatibility is very rare in the US, but ABO incompatibility should be suspected whenever the mother has type O blood and the baby has either type A or B blood and there jaundice.
Yes. Hemolytic disease of the newborn is a collection of disorders that involve circulating immune factors that attach to blood cells and lead to their premature distruction. Although they often produce jaundice as an early sign in the newborn period, they may continue the process of red cell breakdown and lead to jaundice or anemia without jaundice in the first month. Monitoring is needed for all.
Jaundice and anemia. Hemolytic disease of the newborn (hdn) may develop when a mother and her unborn baby have different blood types. The mother produces substances called antibodies that attack the developing baby's red blood cells. The most common form of hdn is ABO incompatibility, which is usually not very severe. The least common form is rh incompatibility, which can be very severe, but can be prevented. Read more...