Does ercp have significant side effects?

ERCP. Yes it can cause pancreatitis, bleeding, infection and perforation. It is crucial that you go to an expert ERCP doctor.
Generally safe. Ercp (endoscopic retrograde cholangiopancreatography) is used to diagnose problems w biliary tract & associated organs (liver, gallbladder, &pancreas).Under sedation a thin fiberoptic camera is threaded down the mouth to duodenum. Complications usually mild but can include pancreatitis(inflammation of pancreas), bleed, infection, perforation. Pretty safe overall; done when benefits outweigh risks.