3 doctors weighed in:
What is the significance of a high AST level?
3 doctors weighed in

Dr. Shaym Puppala
Internal Medicine
2 doctors agree
In brief: Many possibilities
Ast (aspartate aminotransferase) is an enzyme made by liver & muscle which when damaged can leak ast into the bloodstream more than normally.
In addition to liver injury (eg from alcohol, overdoses of meds like acetaminophen, viral hepatitis, med side effects, hemochromatosis, fatty liver), ast can be high occur in thyroid disease, adrenal insufficiency, muscle disease. Sometimes no cause is found.

In brief: Many possibilities
Ast (aspartate aminotransferase) is an enzyme made by liver & muscle which when damaged can leak ast into the bloodstream more than normally.
In addition to liver injury (eg from alcohol, overdoses of meds like acetaminophen, viral hepatitis, med side effects, hemochromatosis, fatty liver), ast can be high occur in thyroid disease, adrenal insufficiency, muscle disease. Sometimes no cause is found.
Dr. Shaym Puppala
Dr. Shaym Puppala
Thank
Get help from a real doctor now
Dr. Marsha Davis
Board Certified, Internal Medicine
24 years in practice
67M people helped
Continue
107,000 doctors available
Read more answers from doctors