Who is mostly at risk for gallstones?

Heredity, Diet, etc. If you have a first-degree relative with gallstones, you have a 5-fold increased risk of developing gallstones. The gallstones that we see most commonly in the US are very rare in non-western countries; we believe this has to do with our high (saturated) fat, high-cholesterol diet. Women have a higher risk of gallstones, especially after pregnancy and estrogen use.
Women. Obese, middle aged, out of shape and a few with chemical- bilirubin issues. Men and others are not immune, just a bit less frequent.