5 doctors weighed in:
What does HDL do to ldl?
5 doctors weighed in

Dr. Luis Villaplana
Internal Medicine
2 doctors agree
In brief: Pacman
Did you ever play pacman? Hdl is the LDL eating pacman.
It helps decrease the total circulating LDL molecules and deliver them to the liver for storage and or disposal. You can not form plaques without inflammation of blood vessel walls and ldl(among other things). So the lower the circulating LDL levels are, the longer it takes to develop blocked arteries.

In brief: Pacman
Did you ever play pacman? Hdl is the LDL eating pacman.
It helps decrease the total circulating LDL molecules and deliver them to the liver for storage and or disposal. You can not form plaques without inflammation of blood vessel walls and ldl(among other things). So the lower the circulating LDL levels are, the longer it takes to develop blocked arteries.
Dr. Luis Villaplana
Dr. Luis Villaplana
Thank
Dr. William Cromwell
Clinical Lipidology
In brief: Influences Risk
Hdl does not directly affect the production or clearance of ldl, although both lipoproteins are important in understanding risk for heart attack and stroke.
Cardiovascular (cvd) risk is related to the number of LDL particles (ldl-p) and the number of HDL particles (hdl-p). Lowering high ldl-p is the primary goal of therapy. When ldl-p is at goal, cvd risk is still high with low hdl-p.

In brief: Influences Risk
Hdl does not directly affect the production or clearance of ldl, although both lipoproteins are important in understanding risk for heart attack and stroke.
Cardiovascular (cvd) risk is related to the number of LDL particles (ldl-p) and the number of HDL particles (hdl-p). Lowering high ldl-p is the primary goal of therapy. When ldl-p is at goal, cvd risk is still high with low hdl-p.
Dr. William Cromwell
Dr. William Cromwell
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Dr. Milton Alvis Jr
Preventive Medicine
In brief: Nothing - Opposites
Lipoproteins are complex particles which carry fat molecules in the water outside cells.
Generally, LDL particles deliver fat molecules into cells; HDL particles can remove fat molecules from cells. Too many LDL particles entering artery walls create problems & wbcs attempt to remove them. Without functioning HDL to remove fat from the wbcs, the wbcs die & this is called atherosclerotic plaque.

In brief: Nothing - Opposites
Lipoproteins are complex particles which carry fat molecules in the water outside cells.
Generally, LDL particles deliver fat molecules into cells; HDL particles can remove fat molecules from cells. Too many LDL particles entering artery walls create problems & wbcs attempt to remove them. Without functioning HDL to remove fat from the wbcs, the wbcs die & this is called atherosclerotic plaque.
Dr. Milton Alvis Jr
Dr. Milton Alvis Jr
Thank
1 comment
Dr. Milton Alvis Jr
The correct issue has always been traffic patterns of fat molecules, not any one fat in particular, such as cholesterol, triglyceride or other fat molecules. Basic science and clinical research data on atherosclerosis (artery disease) has always shown the lipoproteins to be the primary issue and lipoprotein measurements to always correlate with outcome data. However, as of the lat 1970s, the existing methods to measure the lipoproteins were over $5,000/blood sample. Cholesterol (one of the fat molecules the lipoprotein particles carry and manufactured by every single cell in our body) was promoted as a cheaper way to GUESS at the lipoproteins. Why? Because when cholesterol concentrations are very high, they tend to agree with the lipoprotein data. However, when not so high, the agreement is much more variable. When low, cholesterol and lipoprotein measurements are commonly opposite. Thus, if you care about your health and want to avoid major problems before too late, best rely on lipoprotein particle measurements, not cholesterol.
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