How will fat cause coronary artery disease?

LDL Cholesterol. More specifically, LDL (low density lipoprotein) cholesterol gets deposited within the walls of the arteries. These deposits, known as plaque, can continue to build up causing narrowing of the arteries and may lead to blockage. If the involved arteries are in the coronary arteries, this leads to heart disease.
Fat adheres to . The wall of arteries and builds up to eventually pose a risk for blockage and a cascade of events initiated by platelet adherence and aggregation. This subsequently plugs off the artery to prevent blood supply to the heart muscle.